Article
TNFalpha -308 C-->t and -863 C-->a polymorphisms and spermiogram characteristics.
Gynecologic and obstetric investigation - 1 Jan 2008
Kurz Christine, Bentz Eva-Katrin, Denschlag Dominik, Berner Isabel, Keck Christoph, Tempfer Clemens B, Pietrowski Detlef
Abstract excerpt
BACKGROUND: Genetic factors may play a role in male infertility. METHODS: In a prospective case-control study, we assessed the allele and genotype frequencies of the TNFalpha -308 C-->T and -863 C-->A polymorphisms, detected by PCR of sperm DNA, of 577 Caucasian men recruited in an infertility clinic. Semen sampling was performed and spermiogram results were correlated to genetic data. RESULTS: The allele...
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