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Influence of methylenetetrahydrofolate reductase C677T gene polymorphisms in Algerian infertile men with azoospermia or severe oligozoospermia.

Genetic testing and molecular biomarkers - 1 Aug 2012

Chellat Djalila, Rezgoune Mohamed Larbi, Hamane Douadi, Semmame Ouarda, Benlatrèche Cherifa, Abadi Noureddine, Satta Dalila

Abstract excerpt

AIMS: The C677T allele of the methylenetetrahydrofolate reductase (MTHFR) gene has been suggested to represent a risk factor for male infertility. To confirm this association, the distribution of the single-nucleotide polymorphism C677T was investigated in idiopathic infertile Algerian patients with nonobstructive azoospermia (NOA) or severe oligoasthenoteratozoospermia (OAT). A case-control study was carried...

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Identifiers

PMID: 22928696
DOI: 10.1089/gtmb.2011.0367

Genes

MTHFR
OAT

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