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Article

Alpha-1 antichymotrypsin gene signal peptide a/t polymorphism and primary intracerebral hemorrhage.

European neurology - 1 Jan 2008

Dardiotis E, Hadjigeorgiou G M, Dardioti M, Scarmeas N, Paterakis K, Aggelakis K, Komnos A, Tasiou A, Xiromerisiou G, Gabranis I, Zintzaras E, Papadimitriou A, Karantanas A

Abstract excerpt

BACKGROUND/AIMS: Alpha-1 antichymotrypsin (ACT), a serine proteinase inhibitor, has been implicated in vascular pathology. The TT genotype of the ACT signal peptide A/T polymorphism has been reported to confer susceptibility to primary intracerebral hemorrhage (PICH). We conducted a prospective s...

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Identifiers

PMID: 18408372
DOI: 10.1159/000121420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18408372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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