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Gene expression analysis of interferon-β treatment in multiple sclerosis

11 Apr 2008

Abstract excerpt

Treatment with interferon-beta (IFN-beta) induces the expression of hundreds of genes in blood mononuclear cells, and the expression of several genes has been proposed as a marker of the effect of treatment with IFN-beta. However, to date no molecules have been identified that are stably induced by treatment with IFN-beta. We use DNA microarrays to study gene expression in 10 multiple sclerosis (MS) patients who...

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PMID: 18408020
DOI: 10.1177/1352458507085976

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