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Article

Genomic effects of IFN-beta in multiple sclerosis patients.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2003

Weinstock-Guttman Bianca, Badgett Darlene, Patrick Kara, Hartrich Laura, Santos Roseane, Hall Dennis, Baier Monika, Feichter Joan, Ramanathan Murali

Abstract excerpt

The purpose of this report was to characterize the dynamics of the gene expression cascades induced by an IFN-beta-1a treatment regimen in multiple sclerosis patients and to examine the molecular mechanisms potentially capable of causing heterogeneity in response to therapy. In this open-label pharmacodynamic study design, peripheral blood was obtained from eight relapsing-remitting multiple sclerosis patients...

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Topics

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Share to Antigens, Differentiation, T-Lymphocyte
Share to Injections, Intramuscular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-beta

Share to Janus Kinase 1

Share to Lectins, C-Type

Share to Multiple Sclerosis, Relapsing-Remitting

Share to Protein Processing, Post-Translational

Share to Protein-Tyrosine Kinases

Source

Identifiers

PMID: 12928423
DOI: 10.4049/jimmunol.171.5.2694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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