Article
Polymorphisms in platelet glycoprotein 1balpha and factor VII and risk of ischemic stroke: a meta-analysis.
Stroke - 1 Jun 2008
Maguire Jane M, Thakkinstian Ammarin, Sturm Jon, Levi Christopher, Lincz Lisa, Parsons Mark, Whyte Scott, Attia John
Abstract excerpt
BACKGROUND AND PURPOSE: Platelets and components of the coagulation cascade are known to be instrumental in the pathogenesis of arterial occlusive disorders. The aim of this meta-analysis is to test the hypothesis that genetic variation in the platelet glycoprotein 1balpha and Factor VII genes influence the occurrence of ischemic stroke. All genetic association studies that examined the R353Q (rs6046)...
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