Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions.

Science (New York, N.Y.) - 11 Apr 2008

Vartanian Jean-Pierre, Guétard Denise, Henry Michel, Wain-Hobson Simon

Abstract excerpt

Cytidine deaminases of the APOBEC3 family all have specificity for single-stranded DNA, which may become exposed during replication or transcription of double-stranded DNA. Three human APOBEC3A (hA3A), hA3B, and hA3H genes are expressed in keratinocytes and skin, leading us to determine whether genetic editing of human papillomavirus (HPV) DNA occurred. In a study of HPV1a plantar warts and HPV16 precancerous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to APOBEC Deaminases
Share to Cervix Uteri
Share to Cytidine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytidine Deaminase

Share to Cytosine Deaminase

Share to DNA Mismatch Repair

Share to Human papillomavirus 16

Source

Identifiers

PMID: 18403710
DOI: 10.1126/science.1153201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions.PMID 18403710Read ↗

APOBEC3A Functions as a Restriction Factor of Human PapillomavirusSemantic proximity Read ↗

APOBEC3: Friend or Foe in Human Papillomavirus Infection and Oncogenesis?Semantic proximity Read ↗

APOBEC3 Proteins: From Antiviral Immunity to Oncogenic Drivers in HPV-Positive CancersSemantic proximity Read ↗

APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development.Semantic proximity Read ↗

Role of the host restriction factor APOBEC3 on papillomavirus evolutionSemantic proximity Read ↗

APOBEC3A associates with human papillomavirus genome integration in oropharyngeal cancers.Semantic proximity Read ↗

Genetic Editing of Herpes Simplex Virus 1 and Epstein-Barr Herpesvirus Genomes by Human APOBEC3 Cytidine Deaminases in Culture and <i>In Vivo</i>Semantic proximity Read ↗

APOBEC3 Deaminases Induce Hypermutation in Human Papillomavirus 16 DNA upon Beta Interferon StimulationSemantic proximity Read ↗

Human APOBEC3A Isoforms Translocate to the Nucleus and Induce DNA Double Strand Breaks Leading to Cell Stress and DeathSemantic proximity Read ↗

Detection of hypermutated human papillomavirus type 16 genome by Next-Generation Sequencing.Semantic proximity Read ↗

Similar deamination activity but different phenotypic outcomes induced by APOBEC3 enzymes in breast epithelial cellsSemantic proximity Read ↗

HPV11 E6 mutation by overexpression of APOBEC3A and effects of interferon-ω on APOBEC3s and HPV11 E6 expression in HPV11.HaCaT cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.