Article
HPV11 E6 mutation by overexpression of APOBEC3A and effects of interferon-ω on APOBEC3s and HPV11 E6 expression in HPV11.HaCaT cells.
Virology journal - 3 Nov 2017
Wang Yongfang, Li Xinyu, Song Shasha, Sun Yang, Zhang Jiafen, Yu Changming, Chen Wei
Abstract excerpt
BACKGROUND: Condyloma acuminatum, infected by low-risk human papillomaviruses (e.g., HPV6 and HPV11), is one of the most widespread sexually transmitted diseases. Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 proteins (APOBEC3s, A3s) are cellular cytidine deaminases acting as antiviral factors through hypermutation of viral genome. However, it remains unknown whether A3s results in HPV11 gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
