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Article

Genetic differentiation of Escherichia coli O157:H7 clades associated with human disease by real-time PCR.

Journal of clinical microbiology - 1 Jun 2008

Riordan James T, Viswanath Sandeep B, Manning Shannon D, Whittam Thomas S

Abstract excerpt

The rapid and accurate identification of Escherichia coli O157:H7 strains is central to reducing the impact of outbreaks. A real-time PCR-based approach to differentiating major outbreak lineages of O157 with novel single-nucleotide polymorphisms is described. The utility of this method is in detection of hypervirulent strains in cases of clinical disease.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18400915
DOI: 10.1128/JCM.00203-08
PMCID: PMC2446876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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