Article
Use of short tandem repeat sequences to study Mycobacterium leprae in leprosy patients in Malawi and India.
PLoS neglected tropical diseases - 9 Apr 2008
Young Saroj K, Ponnighaus Jorg M, Jain Suman, Lucas Sebastian, Suneetha Sujai, Lockwood Diana N J, Young Douglas B, Fine Paul E M
Abstract excerpt
BACKGROUND: Inadequate understanding of the transmission of Mycobacterium leprae makes it difficult to predict the impact of leprosy control interventions. Genotypic tests that allow tracking of individual bacterial strains would strengthen epidemiological studies and contribute to our understanding of the disease. METHODOLOGY/PRINCIPAL FINDINGS: Genotyping assays based on variation in the copy number of short...
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