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Article

Meta-analysis of homogeneous subgroups reveals association between PDE4D gene variants and ischemic stroke.

Neuroepidemiology - 1 Jan 2011

Yoon Dankyu, Park Sue K, Kang Daehee, Park Taesung, Park Ji Wan

Abstract excerpt

BACKGROUND: An Icelandic study showed a significant positive association between phosphodiesterase 4D (PDE4D) gene variants and stroke. However, subsequent studies reported conflicting results, possibly due to small sample sizes and the heterogeneity of the studies. METHOD: We performed a meta-analysis on 6 SNPs of the PDE4D gene to investigate the association between this gene and ischemic stroke by integrating...

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Identifiers

PMID: 21677445
DOI: 10.1159/000327915

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