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Article

Functional diversification of a protease inhibitor gene in the genus Drosophila and its molecular basis.

Gene - 31 May 2008

Börner Stefan, Ragg Hermann

Abstract excerpt

The mutually exclusive use of alternative reactive site loop (RSL) cassettes due to alternative splicing of serpin (serine protease inhibitor) gene transcripts is a widespread strategy to create target-selective protease inhibitors in the animal kingdom. Since molecular basis and evolution of serpin RSL cassette exon amplification and diversification are unexplored, the exon-intron organization of the serpin gene...

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Identifiers

PMID: 18395367
DOI: 10.1016/j.gene.2008.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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