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Article

Molecular characterization of putative modulatory factors in two Spanish families with A1555G deafness.

Audiology & neuro-otology - 1 Jan 2008

Otaegui D, Irizar H, Goicoechea M, Pérez-Tur J, Belar M, López de Munain A

Abstract excerpt

The aim of this work is to characterize possible modifying factors in 2 large families carrying the A1555G mitochondrial mutation. The heteroplasmy of the mutation, the presence of aminoglycosides, the cosegregation with other mitochondrial mutations, the proposed linkage in chromosome 8 and the association with TRMU and MTO1 genes were studied. None of the mentioned modifying factors were related with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18391568
DOI: 10.1159/000124280

Genes

TRMU
MTO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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