Article
Sex Determination in Birds: <i>HINT</i>s from the W Sex Chromosome?
1 Jan 2007
Abstract excerpt
Sex in birds is controlled genetically (ZZ male: ZW female), but the genetic mechanism remains unclear. While some evidence points to the involvement of Z sex chromosome dosage, other data favour a dominant female-determining gene carried on the W sex chromosome. An intriguing candidate gene located on the chicken W chromosome is HINTW, which encodes an aberrant form of a hydrolase enzyme. In chicken embryos,...
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