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Gene conversion drives the evolution of HINTW, an ampliconic gene on the female-specific avian W chromosome.

Molecular biology and evolution - 1 Oct 2005

Backström Niclas, Ceplitis Helene, Berlin Sofia, Ellegren Hans

Abstract excerpt

The HINTW gene on the female-specific W chromosome of chicken and other birds is amplified and present in numerous copies. Moreover, as HINTW is distinctly different from its homolog on the Z chromosome (HINTZ), is a candidate gene in avian sex determination, and evolves rapidly under positive selection, it shows several common features to ampliconic and testis-specific genes on the mammalian Y chromosome. A...

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PMID: 15972846
DOI: 10.1093/molbev/msi198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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