Article
Opposite roles of<i>DMRT1</i>and its W-linked paralogue,<i>DM-W</i>, in sexual dimorphism of<i>Xenopus laevis</i>: implications of a ZZ/ZW-type sex-determining system
24 Jun 2010
Abstract excerpt
A Y-linked gene, DMY/dmrt1bY, in teleost fish medka and a Z-linked gene, DMRT1, in chicken are both required for male sex determination. We recently isolated a W-linked gene, DM-W, as a paralogue of DMRT1 in Xenopus laevis, which has a ZZ/ZW-type sex-determining system. The DNA-binding domain of DM-W shows high sequence identity with that of DMRT1, but DM-W has no significant sequence similarity with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
