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Functional and Phylogenetic Characterization of Vaginolysin, the Human-Specific Cytolysin from<i>Gardnerella vaginalis</i>

5 Apr 2008

Abstract excerpt

Pore-forming toxins are essential to the virulence of a wide variety of pathogenic bacteria. Gardnerella vaginalis is a bacterial species associated with bacterial vaginosis (BV) and its significant adverse sequelae, including preterm birth and acquisition of human immunodeficiency virus. G. vaginalis makes a protein toxin that generates host immune responses and has been hypothesized to be involved in the...

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PMID: 18390664
DOI: 10.1128/jb.01965-07

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Related research

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Functional and Phylogenetic Characterization of Vaginolysin, the Human-Specific Cytolysin from<i>Gardnerella vaginalis</i>PMID 18390664Read ↗

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Drawing the line between commensal and pathogenic Gardnerella vaginalis through genome analysis and virulence studiesSemantic proximity Read ↗

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