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Article

TRAB: testing whether mutation frequencies are above an unknown background.

Statistical applications in genetics and molecular biology - 1 Jan 2008

Parmigiani Giovanni, Chen Sining

Abstract excerpt

To rigorously determine whether a gene or a set of genes have alterations that are involved in carcinogenesis requires a comparison of the prevalence of identified changes to a control mutation frequency present in tumor DNA. To facilitate this task, we develop a testing approach and the associat...

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PMID: 18384264
DOI: 10.2202/1544-6115.1277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18384264-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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