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Article

HIV-1 drug resistance in HIV-1-infected children in the United Kingdom from 1998 to 2004.

The Pediatric infectious disease journal - 1 May 2008

Chakraborty Rana, Smith Colette J, Dunn David, Green Hannah, Duong Trinh, Doerholt Katja, Riordon Andrew, Lyall Hermione, Tookey Pat, Butler Karina, Sabin Caroline A, Gibb Di, Pillay Deenan

Abstract excerpt

We reviewed HIV-1 genotypes from 200 of 979 (20%) HIV-infected children in the U.K. Collaborative HIV in Pediatric Study (CHIPS) cohort (343 resistance tests). Three of 44 samples had major primary resistance mutations before antiretroviral therapy. Three-class resistance was noted in 42 samples (14.1%). Our study also highlighted underutilization of testing and the need for prompt genotyping after drug...

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PMID: 18382385
DOI: 10.1097/INF.0b013e3181646d6f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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