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Article

Susceptibility to depression expressed as alterations in cortisol day curve: a cross-twin, cross-trait study.

Psychosomatic medicine - 1 Apr 2008

Wichers Marieke C, Myin-Germeys Inez, Jacobs Nele, Kenis Gunter, Derom Catherine, Vlietinck Robert, Delespaul Philippe, Mengelers Ron, Peeters Frenk, Nicolson Nancy, Van Os Jim

Abstract excerpt

OBJECTIVE: To examine, using a cross-twin cross-trait design, the hypotheses 1) that the genetic and environmental susceptibility to depression is expressed, in part, as alterations in cortisol day curves and 2) that cortisol abnormalities are not merely the consequence of depressive states or the stressors associated with its onset. Alteration of diurnal secretion of cortisol is a possible endophenotype of...

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PMID: 18378863
DOI: 10.1097/PSY.0b013e31816b1eee

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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