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Article

Symptoms of major depression: Their stability, familiality, and prediction by genetic, temperamental, and childhood environmental risk factors.

Depression and anxiety - 1 Feb 2017

Kendler Kenneth S, Aggen Steven H

Abstract excerpt

BACKGROUND: Psychiatry has long sought to develop biological diagnostic subtypes based on symptomatic differences. This effort assumes that symptoms reflect, with good fidelity, underlying etiological processes. We address this question for major depression (MD). METHODS: We examine, in twins from a population-based registry, similarity in symptom endorsement in individuals meeting criteria for last-year MD at...

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Identifiers

PMID: 28121394
DOI: 10.1002/da.22591

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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