Article
Carriage of both the fnbA and fnbB genes and growth at 37 °C promote FnBP-mediated biofilm development in meticillin-resistant Staphylococcus aureus clinical isolates
9 Mar 2009
Abstract excerpt
The Staphylococcus aureus FnBPA and FnBPB proteins promote acid-induced biofilm accumulation. Meticillin-resistant S. aureus (MRSA) isolates from device-related infections with both fnbA and fnbB produced significantly more biofilm than isolates with either gene alone. Under mildly acidic growth conditions, FnBP-mediated biofilm and fnbA and fnbB transcript levels were substantially higher during growth at 37...
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