Article
Catalase -262C>T polymorphism in systemic lupus erythematosus in Poland.
Rheumatology international - 1 Aug 2008
Warchoł Teresa, Lianeri Margarita, Wudarski Mariusz, Łacki Jan K, Jagodziński Paweł P
Abstract excerpt
It has been reported that reactive oxygen species contribute to pathogenesis of systemic lupus erythematosus (SLE). Catalase (CAT) -330C>T transition, known also as -262C>T, generates three genotypes. The CAT -330CC genotype is associated with a significantly lower CAT expression in comparison to -330CT and -330CT genotypes. Therefore, using restriction length fragment polymorphism analysis, we compared the...
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