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Article

Cortical enlargement in autism is associated with a functional VNTR in the monoamine oxidase A gene.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008

Davis Lea K, Hazlett Heather C, Librant Amy L, Nopoulos Peggy, Sheffield Val C, Piven Joesph, Wassink Thomas H

Abstract excerpt

Monoamine oxidase A (MAOA) is an enzyme expressed in the brain that metabolizes dopamine, norepinephrine, epinephrine, and serotonin. Abnormalities of serotonin neurotransmission have long been implicated in the psychopathology of autism. A polymorphism exists within the promoter region of the MAOA gene that influences MAOA expression levels so that "low activity" alleles are associated with increased...

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Identifiers

PMID: 18361446
DOI: 10.1002/ajmg.b.30738
PMCID: PMC2752707

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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