Article
Autism severity is associated with child and maternal MAOA genotypes.
Clinical genetics - 1 Apr 2011
Cohen I L, Liu X, Lewis M E S, Chudley A, Forster-Gibson C, Gonzalez M, Jenkins E C, Brown W T, Holden J J A
Abstract excerpt
Autism severity is associated with child and maternal MAOA genotypes. We replicated and extended a previously reported association between autism severity and a functional polymorphism in the monoamine oxidase A (MAOA) promoter region, MAOA-uVNTR, in a sample of 119 males, aged 2-13 years, with autism spectrum disorder from simplex families. We demonstrated that (i) boys with the low activity 3-repeat MAOA allele...
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