Article
Cutaneous microvascular dysfunction is associated with human leukocyte antigen-DQ in youths with type 1 diabetes.
Pediatric research - 1 Apr 2008
Odermarsky Michal, Lernmark Ake, Truedsson Lennart, Liuba Petru
Abstract excerpt
Functional disturbances in microcirculation in juvenile type 1 diabetes (T1D) are believed to underlie, in part, the later occurrence of cardiovascular complications. Some epidemiologic studies suggested greater risk of microvascular complications in those with T1D-risk genotypes of human leukocyte antigen (HLA). We investigated whether HLA-DQ2/8, which is linked to highest T1D morbidity, influences microvascular...
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