Article
Identification of 16S rRNA mutations in Mycoplasma genitalium potentially associated with tetracycline resistance in vivo but not selected in vitro in M. genitalium and Chlamydia trachomatis.
The Journal of antimicrobial chemotherapy - 13 Apr 2021
Le Roy Chloé, Touati Arabella, Balcon Carla, Garraud Justine, Molina Jean-Michel, Berçot Béatrice, de Barbeyrac Bertille, Pereyre Sabine, Peuchant Olivia, Bébéar Cécile
Abstract excerpt
OBJECTIVES: Tetracyclines are widely used for the treatment of bacterial sexually transmitted infections (STIs) and recently have been used successfully for post-exposure prophylaxis of STIs in MSM. We investigated the in vitro and in vivo development of tetracycline resistance in Chlamydia trachomatis and Mycoplasma genitalium and evaluated 16S rRNA mutations associated with acquired resistance in other...
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