The methylenetetrahydrofolate reductase 677C>T gene polymorphism is not associated with chronic plaque psoriasis.

doi:10.1111/j.1600-0625.2008.00713.x

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Article

The methylenetetrahydrofolate reductase 677C>T gene polymorphism is not associated with chronic plaque psoriasis.

Experimental dermatology - 1 Sept 2008

Weger Wolfgang, Hofer Angelika, Stanger Olaf, Wolf Peter, El-Shabrawi Yosuf, Renner Wilfried, Kerl Helmut, Salmhofer Wolfgang

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is involved in the formation of methyl donors, which contribute to DNA methylation. DNA methylation is an essential epigenetic feature playing a critical role in gene regulation and cellular differentiation. In addition, MTHFR activity affects plasma homocysteine levels. A functional polymorphism in the MTHFR gene (677C>T, rs1801133) leading to reduced...

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Identifiers

PMID: 18355300
DOI: 10.1111/j.1600-0625.2008.00713.x

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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The methylenetetrahydrofolate reductase 677C>T gene polymorphism is not associated with chronic plaque psoriasis.PMID 18355300Read ↗

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Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)Semantic proximity Read ↗

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