Article
Human oligodendrocytes express Cx31.3: function and interactions with Cx32 mutants.
Neurobiology of disease - 1 May 2008
Sargiannidou Irene, Ahn Meejin, Enriquez Alan D, Peinado Alejandro, Reynolds Richard, Abrams Charles, Scherer Steven S, Kleopa Kleopas A
Abstract excerpt
Murine oligodendrocytes express the gap junction (GJ) proteins connexin32 (Cx32), Cx47, and Cx29. CNS phenotypes in patients with X-linked Charcot-Marie-Tooth disease may be caused by dominant effects of Cx32 mutations on other connexins. Here we examined the expression of Cx31.3 (the human ortholog of murine Cx29) in human brain and its relation to the other oligodendrocyte GJ proteins Cx32 and Cx47....
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