Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment of cell-cell junctions depends on the oligomeric states of VE-cadherin.

Journal of biochemistry - 1 Jun 2008

Bibert Stéphanie, Ayari Hélène, Riveline Daniel, Concord Evelyne, Hermant Bastien, Vernet Thierry, Gulino-Debrac Danièle

Abstract excerpt

Specifically expressed at intercellular adherens junctions of endothelial cells, VE-cadherin is a receptor that exhibits particular self-association properties. Indeed, in vitro studies demonstrated that the extracellular part of VE-cadherin elaborates Ca(++)-dependent hexameric structures. We hypothesized that this assembly could be at the basis of a new cadherin-mediated cell-cell adhesion mechanism. To verify...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adherens Junctions
Share to Cell Communication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cricetulus

Share to Cross-Linking Reagents

Share to Endothelium, Vascular

Share to Immunoprecipitation

Share to Intercellular Junctions

Share to Umbilical Veins

Source

Open in PubMed Open full text

Identifiers

PMID: 18343874
DOI: 10.1093/jb/mvn035
PMCID: PMC2798001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment of cell-cell junctions depends on the oligomeric states of VE-cadherin.PMID 18343874Read ↗

The molecular organization of endothelial junctions and their functional role in vascular morphogenesis and permeability.Semantic proximity Read ↗

Catenin-dependent and -independent functions of vascular endothelial cadherin.Semantic proximity Read ↗

p120-catenin binding masks an endocytic signal conserved in classical cadherins.Semantic proximity Read ↗

In the first extracellular domain of E-cadherin, heterophilic interactions, but not the conserved His-Ala-Val motif, are required for adhesion.Semantic proximity Read ↗

Ankyrin-G Inhibits Endocytosis of Cadherin Dimers.Semantic proximity Read ↗

Stable vascular connections and remodeling require full expression of VE-cadherin in zebrafish embryos.Semantic proximity Read ↗

VE-cadherin RGD motifs are dispensable for cell-cell junctions, endothelial barrier function and leukocyte extravasationSemantic proximity Read ↗

Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state.Semantic proximity Read ↗

[Molecular functions of seven-pass transmembrane cadherins--homophilic or heterophilic: that is the question].Semantic proximity Read ↗

Heterophilic recognition between E-cadherin and N-cadherin relies on same canonical binding interface as required for E-cadherin homodimerization.Semantic proximity Read ↗

Characterizing interactions in E-cadherin assemblages.Semantic proximity Read ↗

Molecular cloning and characterization of the human E-cadherin cDNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.