Article
P120-catenin is a novel desmoglein 3 interacting partner: identification of the p120-catenin association site of desmoglein 3.
Experimental cell research - 1 May 2008
Kanno Miho, Isa Yasuka, Aoyama Yumi, Yamamoto Yukari, Nagai Miki, Ozawa Masayuki, Kitajima Yasuo
Abstract excerpt
P120-catenin (p120ctn) is an armadillo-repeat protein that directly binds to the intracytoplasmic domains of classical cadherins. p120ctn binding promotes the stabilization of cadherin complexes on the plasma membrane and thus positively regulates the adhesive activity of cadherins. Using co-immunoprecipitation, we show here that p120ctn associates to desmogleins (Dsg) 1 and 3. To determine which region is...
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