Article
Echinococcus granulosus: variability of the host-protective EG95 vaccine antigen in G6 and G7 genotypic variants.
Experimental parasitology - 1 Aug 2008
Chow Conan, Gauci Charles G, Vural Gulay, Jenkins David J, Heath David D, Rosenzvit Mara C, Harandi Majid Fasihi, Lightowlers Marshall W
Abstract excerpt
Cystic hydatid disease in humans is caused by the zoonotic parasite Echinococcus granulosus. As an aid to control transmission of the parasite, a vaccine has been produced for prevention of infection in the parasite's natural animal intermediate hosts. The vaccine utilizes the recombinant oncosphere protein, EG95. An investigation into the genetic variability of EG95 was undertaken in this study to assess...
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