Article
Chromosome-scale Echinococcus granulosus (genotype G1) genome reveals the Eg95 gene family and conservation of the EG95-vaccine molecule.
Communications biology - 3 Mar 2022
Korhonen Pasi K, Kinkar Liina, Young Neil D, Cai Huimin, Lightowlers Marshall W, Gauci Charles, Jabbar Abdul, Chang Bill C H, Wang Tao, Hofmann Andreas, Koehler Anson V, Li Junhua, Li Jiandong, Wang Daxi, Yin Jiefang, Yang Huanming, Jenkins David J, Saarma Urmas, Laurimäe Teivi, Rostami-Nejad Mohammad, Irshadullah Malik, Mirhendi Hossein, Sharbatkhori Mitra, Ponce-Gordo Francisco, Simsek Sami, Casulli Adriano, Zait Houria, Atoyan Hripsime, de la Rue Mario Luiz, Romig Thomas, Wassermann Marion, Aghayan Sargis A, Gevorgyan Hasmik, Yang Bicheng, Gasser Robin B
Abstract excerpt
Cystic echinococcosis is a socioeconomically important parasitic disease caused by the larval stage of the canid tapeworm Echinococcus granulosus, afflicting millions of humans and animals worldwide. The development of a vaccine (called EG95) has been the most notable translational advance in the fight against this disease in animals. However, almost nothing is known about the genomic organisation/location of the...
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