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High polymorphism in genes encoding antigen B from human infecting strains of Echinococcus granulosus

27 Jul 2005

Abstract excerpt

Echinococcus granulosus antigen B (AgB) is encoded by a gene family and is involved in the evasion of the host immune response. E. granulosus exists as a number of strains (G1-G10) that differ in biological characteristics. We used PCR-SSCP followed by DNA sequencing to evaluate sequence variation and transcription profile of AgB in 5 E. granulosus strains. Twenty-four genomic sequences were isolated and...

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PMID: 16336734
DOI: 10.1017/s0031182005008474

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