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Article

Molecular characterization of V59E NIS, a Na+/I- symporter mutant that causes congenital I- transport defect.

Endocrinology - 1 Jun 2008

Reed-Tsur Mia D, De la Vieja Antonio, Ginter Christopher S, Carrasco Nancy

Abstract excerpt

I(-) is actively transported into thyrocytes via the Na+/I(-) symporter (NIS), a key glycoprotein located on the basolateral plasma membrane. The cDNA encoding rat NIS was identified in our laboratory, where an extensive structure/function characterization of NIS is being conducted. Several NIS m...

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Identifiers

PMID: 18339708
DOI: 10.1210/en.2008-0027
PMCID: PMC2408800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18339708-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Molecular characterization of V59E NIS, a Na+/I- symporter mutant that causes congenital I- transport defect.PMID 18339708Read ↗

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