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Article

Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia.

Molecular vision - 4 Mar 2008

Metlapally Ravikanth, Li Yi-Ju, Tran-Viet Khanh-Nhat, Bulusu Anuradha, White Tristan R, Ellis Jaclyn, Kao Daniel, Young Terri L

Abstract excerpt

PURPOSE: The membrane-type frizzled-related protein (MFRP) gene is selectively expressed in the retinal pigment epithelium and ciliary body, and mutations of this gene cause nanophthalmos. The MFRP gene may not be essential for retinal function but has been hypothesized to play a role in ocular axial length regulation. The involvement of the MFRP gene in moderate to high hyperopic, isolated...

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Source

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Identifiers

PMID: 18334955
PMCID: PMC2268852

Genes

MFRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia.PMID 18334955Read ↗

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