Article
Keratocyte phenotype is enhanced in the absence of attachment to the substratum.
Molecular vision - 9 Feb 2008
Funderburgh Martha L, Mann Mary M, Funderburgh James L
Abstract excerpt
PURPOSE: Keratocytes, mesenchymal cells populating the corneal stroma, secrete the unique transparent connective tissue of the cornea as well as opaque scar tissue after injury. Previous studies identified factors mediating keratocyte phenotype in vitro, particularly the expression of the keratan sulfate proteoglycans, which are essential for vision. Whereas earlier work emphasized effects of cytokines, the...
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