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Article

Mosaicism for Trisomy 21 in a Patient With Young-Onset Dementia

1 Mar 2008

Abstract excerpt

OBJECTIVE: To describe a case of young-onset Alzheimer disease (AD) due to mosaicism for trisomy 21. DESIGN: Case report of a single patient. SETTING: Tertiary referral dementia clinic. PATIENT: A 55-year-old man with a mild degree of developmental delay but no previous diagnosis of Down syndrome and only minimal physical manifestations of Down syndrome presented with gradually progressive cognitive impairment...

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PMID: 18332257
DOI: 10.1001/archneur.65.3.412

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