Metabolic phenotype in the brothers of women with polycystic ovary syndrome.

doi:10.2337/dc07-2190

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Article

Metabolic phenotype in the brothers of women with polycystic ovary syndrome.

Diabetes care - 1 Jun 2008

Sam Susan, Coviello Andrea D, Sung Yeon-Ah, Legro Richard S, Dunaif Andrea

Abstract excerpt

OBJECTIVE: Hyperandrogenemia, insulin resistance, and dyslipidemia demonstrate familial aggregation in the female first-degree relatives of women with polycystic ovary syndrome (PCOS), suggesting that these defects are heritable. Hyperandrogenemia also appears to be the male reproductive phenotype. We performed this study to test the hypothesis that brothers of women with PCOS have metabolic defects similar to...

Topics

Adolescent
Adult
Androgens
Blood Glucose
Female
Homeostasis
Humans
Hyperamylasemia
Insulin
Male
Middle Aged
Nuclear Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Patient Selection

Pennsylvania

Phenotype

Polycystic Ovary Syndrome

Reference Values

Siblings

Source

Open in PubMed Open full text

Identifiers

PMID: 18332151
DOI: 10.2337/dc07-2190
PMCID: PMC2897239

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