Evidence for metabolic and reproductive phenotypes in mothers of women with polycystic ovary syndrome.

doi:10.1073/pnas.0602025103

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Article

Evidence for metabolic and reproductive phenotypes in mothers of women with polycystic ovary syndrome.

Proceedings of the National Academy of Sciences of the United States of America - 2 May 2006

Sam Susan, Legro Richard S, Essah Paulina A, Apridonidze Teimuraz, Dunaif Andrea

Abstract excerpt

Dyslipidemia is a feature of polycystic ovary syndrome (PCOS), but its pathogenesis remains controversial. We performed this study of mothers of women with PCOS to test the hypothesis that dyslipidemia is a heritable trait in families of women with PCOS and to investigate the impact of age on reproductive and metabolic phenotypes. Fasting blood was obtained in 215 non-Hispanic white mothers of women with PCOS and...

Topics

Adolescent
Adult
Age Factors
Blood Glucose
Cholesterol, LDL
Dyslipidemias
Energy Metabolism
Female
Humans
Menstruation
Metabolic Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mothers

Obesity

Phenotype

Polycystic Ovary Syndrome

Reproduction

Testosterone

Source

Open in PubMed Open full text

Identifiers

PMID: 16632599
DOI: 10.1073/pnas.0602025103
PMCID: PMC1459013

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