Article
The relationship between ACE genotype and risk of severe hypoglycaemia in a large population-based cohort of children and adolescents with type 1 diabetes.
Diabetologia - 1 May 2007
Bulsara M K, Holman C D J, van Bockxmeer F M, Davis E A, Gallego P H, Beilby J P, Palmer L J, Choong C, Jones T W
Abstract excerpt
AIMS/HYPOTHESIS: Genetic factors may account for familial clustering related to diabetes complications. Studies have shown a significant relationship between the presence of the deletion (D) allele of the gene encoding ACE and risk of severe hypoglycaemia. This large prospective cohort study assesses this relationship in a large sample of children and adolescents with type 1 diabetes. SUBJECTS AND METHODS: We...
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