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Article

Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline-soma interactions in mice

6 Mar 2008

Abstract excerpt

In mammals, the supporting cell lineage in an embryonic gonad communicates the sex-determining decision to various sexually dimorphic cell types in the developing embryo, including the germ cells. However, the molecular nature of the sex-determining signals that pass from the supporting cells to the germ cells is not well understood. We have identified a conserved transmembrane protein, Sdmg1, owing to its...

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PMID: 18321981
DOI: 10.1242/dev.019497

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