Article
Global meta-analysis of the C-11377G alteration in the ADIPOQ gene indicates the presence of population-specific effects: challenge for global health initiatives.
The pharmacogenomics journal - 1 Feb 2009
Schwarz P E H, Towers G W, van der Merwe A, Perez-Perez L, Rheeder P, Schulze J, Bornstein S R, Licinio J, Wong M-L, Schutte A E, Olckers A
Abstract excerpt
Type II diabetes mellitus is currently globally one of the fastest growing non-communicable diseases, especially in developing countries. This investigation reports on a meta-analysis undertaken of the C-11377G locus within the adiponectin gene in a black South African, a Cuban Hispanic and a German Caucasian cohort. Genotyping was performed via a real-time PCR strategy. Both fixed- and random-effects models were...
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