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Article

Hyper- and hyporesponsive mutant forms of the Saccharomyces cerevisiae Ssy1 amino acid sensor.

Molecular membrane biology - 1 Feb 2008

Poulsen Peter, Gaber Richard F, Kielland-Brandt Morten C

Abstract excerpt

The Saccharomyces cerevisiae integral membrane protein Ssy1p functions with Ssy5p and Ptr3p to sense extracellular amino acids. Signal transduction leads to processing and nuclear localization of Stp1p and Stp2p, transcriptional activators of many amino acid transporter genes. Ssy1p is structurally related to amino acid permeases, but unable to transport amino acids. We isolated SSY1 mutants that constitutively...

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Identifiers

PMID: 18307103
DOI: 10.1080/09687680701771917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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