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Article

Molecular testing for somatic cancer mutations: a survey of current and future testing in UK laboratories.

Journal of clinical pathology - 1 Mar 2008

Wordsworth S, Papanicolas I, Buchanan J, Frayling I, Taylor J, Tomlinson I

Abstract excerpt

BACKGROUND: Genetics clinical practice has paid limited attention to non-inherited aspects of cancer, namely mutations occurring during carcinogenesis. These somatic mutations are likely to be the primary determinants of cancer behaviour and treatment response, with a recent example being Her2/Neu gene status and response to Herceptin in breast cancer. AIM: To assess the feasibility of widespread testing of...

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PMID: 18305182
DOI: 10.1136/jcp.2007.048819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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