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Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology.

British journal of cancer - 1 Jan 2026

Phillips Richard, Basu Bristi, Butt Zohra, Beloueche Mounia, Cook Natalie, Crabb Simon J, Greystoke Alastair, Hargrave Darren, Jones Robert, Kureeman Muhammad Yasin, Lopez Juanita, McKeeve Claire, Meissner Magdalena, O'Carrigan Brent, Parkes Eileen E, Ronghe Milind, Roxburgh Patricia, Sarker Debashis, Savage Kienan I, Shaw Paul H S, Symeonides Stefan, Tweddle Deborah A, Vedi Aditi, Walter Harriet S, Zabkiewicz Joanna, Middleton Gary W, Beggs Andrew D

Abstract excerpt

BACKGROUND: The Experimental Cancer Medicine Centre (ECMC) Network supports UK-wide access to experimental cancer therapies, many of which require specific genomic alterations. This study aimed to develop expert consensus on essential genes for a pan-cancer sequencing panel, involving subject matter experts (SMEs) from the ECMC Network and the pharmaceutical industry. METHODS: A pilot with 8 SMEs graded 526...

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Biomarkers, Tumor
Consensus Sequence
DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Instability

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PMID: 41206382
DOI: 10.1038/s41416-025-03252-6
PMCID: PMC12820137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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