Article
The role of CYP2D6*4 variant in bladder cancer susceptibility in Tunisian patients.
Bulletin du cancer - 1 Feb 2008
Ouerhani Slah, Marrakchi Raja, Bouhaha Rym, Ben Slama Mohamed Riadh, Sfaxi Mohamed, Ayed Mohsen, Chebil Mohamed, El Gaaied Amel Ben Ammar
Abstract excerpt
CYP2D6 enzyme is implicated in the metabolism of drugs and nicotine. Genetic variability within CYP2D6, results in different CYP2D6 phenotypes. Inheritance of polymorphic CYP2D6 metabolizing enzyme is likely to be an important determinant of inter-individual variations in susceptibility to cancer. In this work, we have conducted a case control study in order to assess the role of CYP2D6*4 variant in bladder...
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