Article
Characteristic immunophenotyping artefact seen in patients with anti-mouse immunoglobulin antibodies.
Cytometry - 1 Jan 1990
Wilks D, Byrom N, Walker L, Habeshaw J, Dalgleish A
Abstract excerpt
Patients treated with murine monoclonal antibodies develop anti-mouse immunoglobulin antibodies which can interfere with flow cytometry of lymphocytes, giving rise to high levels of nonspecific staining. This artefact can be avoided by using separated, washed lymphocytes for immunophenotyping.
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