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Article

Characteristic immunophenotyping artefact seen in patients with anti-mouse immunoglobulin antibodies.

Cytometry - 1 Jan 1990

Wilks D, Byrom N, Walker L, Habeshaw J, Dalgleish A

Abstract excerpt

Patients treated with murine monoclonal antibodies develop anti-mouse immunoglobulin antibodies which can interfere with flow cytometry of lymphocytes, giving rise to high levels of nonspecific staining. This artefact can be avoided by using separated, washed lymphocytes for immunophenotyping.

Topics

Animals
Antibodies, Anti-Idiotypic
Antibodies, Monoclonal
CD4 Antigens
Flow Cytometry
HIV Infections
Humans
Immunotherapy
Mice
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2318086
DOI: 10.1002/cyto.990110215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2318086-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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