Article
Fas-associated factor (FAF1) is required for the early cleavage-stages of mouse embryo.
Molecular human reproduction - 1 Apr 2008
Adham Ibrahim M, Khulan Janchiv, Held Torsten, Schmidt Bernhardt, Meyer Barbara I, Meinhardt Andreas, Engel Wolfgang
Abstract excerpt
FAF1 was initially isolated as a Fas-associated factor and was subsequently found to interact with a subset of additional proteins that are involved in many cellular events including Fas-mediated apoptosis, heat shock signalling pathways and ubiquitin-dependent processes. Here, we describe that the 74-kDa FAF1 is ubiquitously expressed, while the expression of its post-translational-processed 49-kDa isoform is...
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