Article
Rearrangement of the T-cell receptor delta chain gene in T-cell lymphomas with a mature phenotype.
The American journal of pathology - 1 Jul 1991
van Krieken J H, Elwood L, Andrade R E, Jaffe E S, Cossman J, Medeiros L J
Abstract excerpt
The configuration of the T-cell receptor (TCR) delta chain gene was assessed using restriction fragment analysis and the Southern blot technique in 39 T-cell lymphomas with a mature immunophenotype. The TCR delta gene was rearranged in four lymphomas although the gamma/delta TCR was not expressed...
Topics
- Chromosome Deletion
- Gene Rearrangement, T-Lymphocyte
- Humans
- Lymphoma, T-Cell
- Phenotype
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, gamma-delta
- T-Lymphocytes